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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS2180 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS2180, RRID:AB_1663687
- Product name
- SR 1A (F321) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 291-340 of Human SR-1A.
- Description
- The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. ÉÇ-adrenergic bound to adrenaline activates adenylyl cyclase, while Ï«2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the Ï«2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories,designated SR-1ÿ7 (5HT1ÿ7). Subtypes within the SR-1 group include SR-1A,-1B, -1D, -1E and -1F.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of SR-1A (F321) pAb at 1:500 dilutionLane1:HepG2 whole cell lysateLane2:NIH-3T3 whole cell lysateLane3:H9C2 whole cell lysate
