Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN2841890 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A) (AA 535-566), (Center) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 535-566, Center
- Antibody clone number
- RB14591
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A.
Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding.
Human neuroma contains increased levels of semaphorin 3A, which surrounds nerve fibers and reduces neurite extension in vitro.
Narazaki M, Segarra M, Tosato G
Blood 2008 Apr 15;111(8):4126-36
Blood 2008 Apr 15;111(8):4126-36
Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding.
Appleton BA, Wu P, Maloney J, Yin J, Liang WC, Stawicki S, Mortara K, Bowman KK, Elliott JM, Desmarais W, Bazan JF, Bagri A, Tessier-Lavigne M, Koch AW, Wu Y, Watts RJ, Wiesmann C
The EMBO journal 2007 Nov 28;26(23):4902-12
The EMBO journal 2007 Nov 28;26(23):4902-12
Human neuroma contains increased levels of semaphorin 3A, which surrounds nerve fibers and reduces neurite extension in vitro.
Tannemaat MR, Korecka J, Ehlert EM, Mason MR, van Duinen SG, Boer GJ, Malessy MJ, Verhaagen J
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Dec 26;27(52):14260-4
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 Dec 26;27(52):14260-4
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC