MAB1250

antibody from R&D Systems

Targeting: SEMA3A coll-1, Hsema-I, SEMA1, SEMAD, SemD

Western blot (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

MAB1250

Provider

R&D Systems

Product name

Human Semaphorin 3A Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human Semaphorin 3A in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human Semaphorin 3B, 3E, 6A, 6B, 6C, 6D, 7A, recombinant mouse Semaphorin 3C, or 3F is observed.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

Q14563


Isotype

IgG

Antibody clone number

215803

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

B7-H4 Modulates Regulatory CD4⁺ T Cell Induction and Function via Ligation of a Semaphorin 3a/Plexin A4/Neuropilin-1 Complex.

Podojil JR, Chiang MY, Ifergan I, Copeland R, Liu LN, Maloveste S, Langermann S, Liebenson D, Balabanov R, Chi H, Chen L, Vignali DAA, Miller SD
Journal of immunology (Baltimore, Md. : 1950) 2018 Aug 1;201(3):897-907

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Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A.

Giacobini P, Parkash J, Campagne C, Messina A, Casoni F, Vanacker C, Langlet F, Hobo B, Cagnoni G, Gallet S, Hanchate NK, Mazur D, Taniguchi M, Mazzone M, Verhaagen J, Ciofi P, Bouret SG, Tamagnone L, Prevot V
PLoS biology 2014 Mar;12(3):e1001808

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Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model.

Chakraborty G, Kumar S, Mishra R, Patil TV, Kundu GC
PloS one 2012;7(3):e33633

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Measles virus modulates dendritic cell/T-cell communication at the level of plexinA1/neuropilin-1 recruitment and activity.

Tran-Van H, Avota E, Börtlein C, Mueller N, Schneider-Schaulies S
European journal of immunology 2011 Jan;41(1):151-63