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LearnBS4032
antibody from Bioworld Technology, Inc
Targeting: CCR5
CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS4032 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CKR 5 (phospho S349) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic phosphopeptide derived from human CKR-5 around the phosphorylation site of Serine 349.
- Description
- The CC chemokine receptor 5 (CCR5) is a member of the CC-chemokine receptor family, and has the characteristic structure of a 7 transmembrane G protein-coupled receptor (GPCR). CCR5 regulates trafficking and effector functions of memory/effector Th1 cells, macrophages, NK cells, and immature dendritic cells. CCR5 and its ligands play an important role in viral pathogenesis. CCR5 represents the co-receptor for macrophage (M) and dual (T cell and M)-tropic immunodeficiency viruses. Together with the CD4 binding receptor, CCR5 plays a critical role in HIV entry into the target cells.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of p-CKR-5 (S349) pAb at 1:500 dilutionLane1:Hela cell lysate treated with PMA(100nM,15mins)Lane2:sp2/0 cell lysate treated with PMA(100nM,15mins)Lane3:PC12 cell lysate treated with PMA(100nM,15mins)
