Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 15542-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15542-1-AP, RRID:AB_2146189
- Product name
- MRPL49 antibody
- Antibody type
- Polyclonal
- Description
- MRPL49 antibody (Cat. #15542-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition.
Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB.
Human Mitochondrial DNA-Protein Complexes Attach to a Cholesterol-Rich Membrane Structure.
Largen: a molecular regulator of mammalian cell size control.
Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication.
C7orf30 specifically associates with the large subunit of the mitochondrial ribosome and is involved in translation.
Busch JD, Cipullo M, Atanassov I, Bratic A, Silva Ramos E, Schöndorf T, Li X, Pearce SF, Milenkovic D, Rorbach J, Larsson NG
Cell reports 2019 Nov 5;29(6):1728-1738.e9
Cell reports 2019 Nov 5;29(6):1728-1738.e9
Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB.
Hensen F, Potter A, van Esveld SL, Tarrés-Solé A, Chakraborty A, Solà M, Spelbrink JN
Nucleic acids research 2019 Apr 23;47(7):3680-3698
Nucleic acids research 2019 Apr 23;47(7):3680-3698
Human Mitochondrial DNA-Protein Complexes Attach to a Cholesterol-Rich Membrane Structure.
Gerhold JM, Cansiz-Arda Ş, Lõhmus M, Engberg O, Reyes A, van Rennes H, Sanz A, Holt IJ, Cooper HM, Spelbrink JN
Scientific reports 2015 Oct 19;5:15292
Scientific reports 2015 Oct 19;5:15292
Largen: a molecular regulator of mammalian cell size control.
Yamamoto K, Gandin V, Sasaki M, McCracken S, Li W, Silvester JL, Elia AJ, Wang F, Wakutani Y, Alexandrova R, Oo YD, Mullen PJ, Inoue S, Itsumi M, Lapin V, Haight J, Wakeham A, Shahinian A, Ikura M, Topisirovic I, Sonenberg N, Mak TW
Molecular cell 2014 Mar 20;53(6):904-15
Molecular cell 2014 Mar 20;53(6):904-15
Replication factors transiently associate with mtDNA at the mitochondrial inner membrane to facilitate replication.
Rajala N, Gerhold JM, Martinsson P, Klymov A, Spelbrink JN
Nucleic acids research 2014 Jan;42(2):952-67
Nucleic acids research 2014 Jan;42(2):952-67
C7orf30 specifically associates with the large subunit of the mitochondrial ribosome and is involved in translation.
Wanschers BF, Szklarczyk R, Pajak A, van den Brand MA, Gloerich J, Rodenburg RJ, Lightowlers RN, Nijtmans LG, Huynen MA
Nucleic acids research 2012 May;40(9):4040-51
Nucleic acids research 2012 May;40(9):4040-51
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- BxPC-3 cells were subjected to SDS PAGE followed by western blot with 15542-1-AP(MRPL49 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 15542-1-AP(MRPL49 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MRPL49 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MRPL49. This antibody recognizes human antigen. The MRPL49 antibody has been validated for the following applications: ELISA, WB, IHC analysis.