10-4165

antibody from ABEOMICS Inc.
Targeting: MUL1 C1orf166, FLJ12875, GIDE, MAPL, MULAN, RNF218
Provider product page for 10-4165

Antibody data

Product number
10-4165 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-MUL1 Antibody
Antibody type
Monoclonal
Description
MUL1 (Mitochondrial E3 Ubiquitin Protein Ligase-1) is a crucial moderator of RIG-I (Retinoic Acid-Inducible-Gene-I) signaling. This protein is localized to the mitochondria where it interacts with MAVS (Mitochondrial Antiviral Signaling) and catalyzes RIG-I post-translational modifications that inhibit RIG-I-dependent cell signaling. MUL1 contains a unique BAM (Beside A Membrane) domain and a C-terminal RING-finger domain. This protein has been implicated in several processes that occur in animal cells such as NF-KappaB activation, innate immunity and antiviral signaling, suppression of PINK1/parkin defects, mitophagy in skeletal muscle, and caspase-dependent apoptosis.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
A partial length recombinant MUL1 p
rotein (amino acids 146-352) was us
ed as the immunogen for this antibo
dy.
Isotype
IgG
Antibody clone number
ABM4F71
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
MUL1 protein structure - 10-4165 shown in red.