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- Product number
- ABIN1450109 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Signal-Induced Proliferation-Associated 1 (SIPA1) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- 19 amino acid synthetic peptide from near the amino terminus of human SIPA1
- Description
- Affinity chromatography purified via peptide column
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Spa-1 (Sipa1) and Rap signaling in leukemia and cancer metastasis.
Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice.
Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product.
Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression.
Minato N, Hattori M
Cancer science 2009 Jan;100(1):17-23
Cancer science 2009 Jan;100(1):17-23
Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice.
Ishida D, Kometani K, Yang H, Kakugawa K, Masuda K, Iwai K, Suzuki M, Itohara S, Nakahata T, Hiai H, Kawamoto H, Hattori M, Minato N
Cancer cell 2003 Jul;4(1):55-65
Cancer cell 2003 Jul;4(1):55-65
Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product.
Kurachi H, Wada Y, Tsukamoto N, Maeda M, Kubota H, Hattori M, Iwai K, Minato N
The Journal of biological chemistry 1997 Oct 31;272(44):28081-8
The Journal of biological chemistry 1997 Oct 31;272(44):28081-8
Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression.
Hattori M, Tsukamoto N, Nur-e-Kamal MS, Rubinfeld B, Iwai K, Kubota H, Maruta H, Minato N
Molecular and cellular biology 1995 Jan;15(1):552-60
Molecular and cellular biology 1995 Jan;15(1):552-60
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of SIPA1 in human brain tissue lysate with SIPA1 antibody at 1 ?g/mL.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunofluorescence of SIPA1 in human brain cells with SIPA1 antibody at 20 ug/mL.
