Explore
Validate
LearnGTX30123
antibody from GeneTex
Targeting: EPAS1
bHLHe73, HIF2A, HLF, MOP2, PASD2
Western blot
ELISA Immunocytochemistry Immunoprecipitation Immunohistochemistry Flow cytometry Gel shift Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- GTX30123 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX30123, RRID:AB_386038
- Product name
- HIF2 alpha antibody [ep190b]
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse, Rat, Hamster
- Host
- Mouse
Submitted references Changes in cell fate determine the regenerative and functional capacity of the developing kidney before and after release of obstruction.
Thiamine deficiency activates hypoxia inducible factor-1α to facilitate pro-apoptotic responses in mouse primary astrocytes.
VHL and PTEN loss coordinate to promote mouse liver vascular lesions.
Identification of Ror2 as a hypoxia-inducible factor target in von Hippel-Lindau-associated renal cell carcinoma.
ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress.
VHL type 2B mutations retain VBC complex form and function.
Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I.
Nagalakshmi VK, Li M, Shah S, Gigliotti JC, Klibanov AL, Epstein FH, Chevalier RL, Gomez RA, Sequeira-Lopez MLS
Clinical science (London, England : 1979) 2018 Dec 12;132(23):2519-2545
Clinical science (London, England : 1979) 2018 Dec 12;132(23):2519-2545
Thiamine deficiency activates hypoxia inducible factor-1α to facilitate pro-apoptotic responses in mouse primary astrocytes.
Zera K, Zastre J
PloS one 2017;12(10):e0186707
PloS one 2017;12(10):e0186707
VHL and PTEN loss coordinate to promote mouse liver vascular lesions.
Chen S, Sanford CA, Sun J, Choi V, Van Dyke T, Samulski RJ, Rathmell WK
Angiogenesis 2010 Mar;13(1):59-69
Angiogenesis 2010 Mar;13(1):59-69
Identification of Ror2 as a hypoxia-inducible factor target in von Hippel-Lindau-associated renal cell carcinoma.
Wright TM, Rathmell WK
The Journal of biological chemistry 2010 Apr 23;285(17):12916-24
The Journal of biological chemistry 2010 Apr 23;285(17):12916-24
ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress.
Myers K, Gagou ME, Zuazua-Villar P, Rodriguez R, Meuth M
PLoS genetics 2009 Jan;5(1):e1000324
PLoS genetics 2009 Jan;5(1):e1000324
VHL type 2B mutations retain VBC complex form and function.
Hacker KE, Lee CM, Rathmell WK
PloS one 2008;3(11):e3801
PloS one 2008;3(11):e3801
Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I.
Catrina SB, Botusan IR, Rantanen A, Catrina AI, Pyakurel P, Savu O, Axelson M, Biberfeld P, Poellinger L, Brismar K
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Aug 1;12(15):4506-14
Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Aug 1;12(15):4506-14
No comments: Submit comment
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Western Blot: HIF-2 alpha Antibody (ep190b) (GTX30123) - HIF-2 alpha detected in hypoxic human lysate using GTX30123. Lane 1: normoxic A549 lysate control, lane 2: hypoxic A549 lysate.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemistry: HIF-2 alpha Antibody (ep190b) (GTX30123) - Staining of heart, cardiac myocytes
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Flow Cytometry: HIF-2 alpha Antibody (ep190b) (GTX30123) - HIF-2 alpha antibody was tested at 1:400 in HepG2 cells using an Alexa Fluor 488 secondary (shown in purple). M1 is defined by unstained cells.
