BS60235

antibody from Bioworld Technology, Inc
Targeting: RHOQ ARHQ, RASL7A, TC10
Provider product page for BS60235

Antibody data

Product number
BS60235 - Provider product page
Provider
Bioworld Technology, Inc
Product name
RHOQ polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human RHOQ.
Description
tc10 is a small GTP-binding protein that is induced during nerve injury, where it cooperates with other Rho family members to facilitate nerve regeneration and, in particular, neurite elongation. tc10 is located predominantly in the plasma membrane, a property that depends both on its post-translational prenylation and on its ability to bind and hydrolyze GTP. tc10 colocalizes to actin filaments and interacts with the actin-binding and filament-forming protein, profilin. tc10 functions to regulate cellular signaling to the actin cytoskeleton and processes associated with cell growth. tc10 also interacts with a similar subset of effectors for Cdc42 and is regulated differentially by p50Rho GTPase-activating protein. Activated tc10 interacts with a variety of putative Rho family effectors, stimulates JNK, and induces filopodial formation.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RHOQ protein structure - BS60235 shown in red.