BS8325

antibody from Bioworld Technology, Inc

Targeting: MAT1A MAT, MATA1, SAMS, SAMS1

Immunohistochemistry

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Validation data

Product number: BS8325 - Provider product page
Provider: Bioworld Technology, Inc
Product name: MAT1A polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human MAT1A.
Description: Methionine adenosyltransferase (MAT) catalyzes the formation of S-adenosyltransferase (AdoMet) for methionine catabolism in the liver. Two different genes, MAT1A and MAT2A, encode a liver specific and non-liver specific form of MAT, designated MAT IÏ« and MAT IIÏ«, respectively. Inactivation of the liver specific gene product, designated MAT I/III, associates with liver diseases such as cirrhosis. MAT IÏ« expression also correlates with a differentiated phenotype, whereas liver cells expressing MAT IIÏ« present a dedifferentiated phenotype and lowered AdoMet synthesis. Likewise, NF-kB and TNFÏ« cause a switch from MAT IÏ« to MAT IIÏ« expression in human hepatocellular carcinoma (HCC), which facilitates cancer cell growth.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

MAT1A protein structure - BS8325 shown in red.