H00030816-M06

antibody from Abnova Corporation

Targeting: ERVW-1 envW, ERVWE1, HERV-7q, HERV-W, HERV-W-ENV, HERVW

ELISA (Supportive data in Antibodypedia)

Antibody Data

Product number

H00030816-M06

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#H00030816-M06, RRID:AB_875559

Product name

ERVWE1 monoclonal antibody (M06), clone 4F10

Antibody type

Monoclonal

Description

Mouse monoclonal antibody raised against a partial recombinant ERVWE1.

Antigen sequence

DGGGVQDQAREKHVKEVISQLTRVHGTSSPYKGLD
LSKLHETLRTHTRLVSLFNTTLTGLHEVSAQNPTN
CWICLPLNFRPYVSIPVPEQWNNFSTEINT


Isotype

IgG

Antibody clone number

4F10

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Regulation of the human endogenous retroviral Syncytin-1 and cell-cell fusion by the nuclear hormone receptors PPARγ/RXRα in placentogenesis.

Ruebner M, Langbein M, Strissel PL, Henke C, Schmidt D, Goecke TW, Faschingbauer F, Schild RL, Beckmann MW, Strick R
Journal of cellular biochemistry 2012 Jul;113(7):2383-96

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Impaired cell fusion and differentiation in placentae from patients with intrauterine growth restriction correlate with reduced levels of HERV envelope genes.

Ruebner M, Strissel PL, Langbein M, Fahlbusch F, Wachter DL, Faschingbauer F, Beckmann MW, Strick R
Journal of molecular medicine (Berlin, Germany) 2010 Nov;88(11):1143-56

ELISA

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Detection limit for recombinant GST tagged ERVWE1 is approximately 0.1ng/ml as a capture antibody.

Validation comment

Sandwich ELISA (Recombinant protein)

Protocol

Protocol