ABIN526263

antibody from antibodies-online

Targeting: ERVW-1 envW, ERVWE1, HERV-7q, HERV-W, HERV-W-ENV, HERVW

ELISA (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN526263

Provider

antibodies-online

Product name

anti-Endogenous Retrovirus Group W, Member 1 (ERVW-1) (AA 116-215) antibody

Antibody type

Monoclonal

Antigen

ERVWE1 (NP_055405, 116 a.a. ~ 215 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: DGGGVQDQAREKHVKEVISQ LTRVHGTSSPYKGLDLSKLH ETLRTHTRLVSLFNTTLTGL HEVSAQNPTNCWICLPLNFR PYVSIPVPEQWNNFSTEINT

Reactivity

Human

Host

Mouse

Epitope

AA 116-215

Isotype

IgG

Antibody clone number

4F10

Vial size

100 μg

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Regulation of the human endogenous retroviral Syncytin-1 and cell-cell fusion by the nuclear hormone receptors PPARγ/RXRα in placentogenesis.

Ruebner M, Langbein M, Strissel PL, Henke C, Schmidt D, Goecke TW, Faschingbauer F, Schild RL, Beckmann MW, Strick R
Journal of cellular biochemistry 2012 Jul;113(7):2383-96

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Impaired cell fusion and differentiation in placentae from patients with intrauterine growth restriction correlate with reduced levels of HERV envelope genes.

Ruebner M, Strissel PL, Langbein M, Fahlbusch F, Wachter DL, Faschingbauer F, Beckmann MW, Strick R
Journal of molecular medicine (Berlin, Germany) 2010 Nov;88(11):1143-56

ELISA

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Detection limit for recombinant GST tagged ERVWE1 is approximately 0.1ng/ml as a capture antibody.