APR03864G

antibody from Leading Biology

Targeting: CELA3B CBPP, ELA3B

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR03864G

Provider

Leading Biology

Product name

CELA3B Antibody (N-term)

Antibody type

Polyclonal

Description

Elastases form a subfamily of serine proteases thathydrolyze many proteins in addition to elastin. Humans have sixelastase genes which encode the structurally similar proteinselastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase3B has little elastolytic activity. Like most of the humanelastases, elastase 3B is secreted from the pancreas as a zymogenand, like other serine proteases such as trypsin, chymotrypsin andkallikrein, it has a digestive function in the intestine. Elastase3B preferentially cleaves proteins after alanine residues. Elastase3B may also function in the intestinal transport and metabolism ofcholesterol. Both elastase 3A and elastase 3B have been referred toas protease E and as elastase 1, and excretion of this protein infecal material is frequently used as a measure of pancreaticfunction in clinical assays.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.