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- Antigen structure
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- Product number
- PA1-16586 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CTR1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Suggested positive control: human breast cancer and kidney tissue.
- Reactivity
- Human, Mouse, Rat, Canine, Porcine, Xenopus, Zebrafish
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Promotion of cadmium uptake and cadmium-induced toxicity by the copper transporter CTR1 in HepG2 and ZFL cells.
Kwok ML, Li ZP, Law TYS, Chan KM
Toxicology reports 2020;7:1564-1570
Toxicology reports 2020;7:1564-1570
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of CTR1 in hCTR1 overexpressing cell line. Samples were incubated in CTR1 polyclonal antibody (Product # PA1-16586). Left panel: Antibody. Right panel: Antibody plus peptide competition staining.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of CTR1 in breast cancer tissue. Samples were incubated in CTR1 polyclonal antibody (Product # PA1-16586). Panel 1: human CTR1 staining of breast cancer tissue. Panel 2: human CTR1-antigen competition in breast cancer tissue.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Fig. 3 Immunofluorescence determination of hCTR1 subcellular localization in HepG2 cells in the presence or absence of Cd 2+ . Nuclei were stained with DAPI (S36973; Invitrogen), and CTR1 were probed with Alexa-488 anti-rabbit antibody. (A) Control, in the absence of Cd 2+ exposure. Scale bar, 10 mum. (B) Following exposure to 1 muM Cd 2+ for 24 h. Scale bar, 10 mum. (C) Zoom of HepG2 cells following Cd 2+ exposure. 3 x zoom; scale bar, 5 mum. (D) Zoom of another image frame following Cd 2+ exposure. 3 x zoom; scale bar, 5 mum. Fig. 3
