FNab07239

antibody from FineTest Biotech
Targeting: RNLS C10orf59, FLJ11218, renalase
Provider product page for FNab07239
Western blot
ELISA
Immunohistochemistry

Antibody data

Product number
FNab07239 - Provider product page
Provider
FineTest Biotech
Product name
RENALASE antibody
Antibody type
Monoclonal
Antigen
Recombinant protein fragment
Description
RNLS, also named as Renalase, C10orf59 and MAO-C, belongs to the renalase family. It is probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. RNLS degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. RNLS has physiologically relevant catecholamine-oxidizing activity.(PMID:15841207) This antibody is specific to RNLS.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
chromosome 10 open reading frame 59
Epitope
IgG1
Isotype
IgG
Antibody clone number
9C9
Vial size
100¦Ìg
Concentration
Protein A+G purification
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
RNLS protein structure - FNab07239 shown in red.