CABT-BL2986

antibody from Creative Diagnostics

Targeting: PPP2R5D B56D, B56delta

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

CABT-BL2986

Provider

Creative Diagnostics

Product name

Anti-PPP2R5D monoclonal antibody, clone 2B4

Antibody type

Monoclonal

Description

B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2B4

Storage

Store at -2°C or lower. Aliquot to avoid repeated freezing and thawing.