BS8300

antibody from Bioworld Technology, Inc
Targeting: HOXB1 HOX2, HOX2I
Provider product page for BS8300
Western blot
Immunohistochemistry

Antibody data

Product number
BS8300 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HOXB1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HOXB1.
Description
HOX genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene Hoxb-1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of Hoxb-1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). Hoxb-1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the sonic hedgehog and Mash1 signaling pathways. Hoxb2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. Hoxb2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, Hoxb2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HOXB1 protein structure - BS8300 shown in red.