Antibody data

Product number
11-3028-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-IMPDHII Antibody
Antibody type
Polyclonal
Description
Human type II inosine monophosphate dehydrogenase (IMPDHII) is a key enzyme in the purine nucleotide biosynthetic pathway and constitutes a pivotal biological target for immunosuppressant and antiviral drugs. It is linked to cell growth, differentiation, and malignant transformation. IMPDHII also plays an important role in the negative regulation of TLR2 signaling by modulating PI3K activity. Indeed, IMPDHII increases the phosphatase activity of SHP1, which participates in the inactivation of PI3K. Enhanced expression of IMPDHII promotes the tumor metastasis and the advanced tumor progression in patients with prostate cancer.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant IMPDHI
I protein (amino acids 86-291) was
used as the immunogen for this anti
body.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
IMPDH2 protein structure - 11-3028-25 shown in red.