11-10038

antibody from ABEOMICS Inc.
Targeting: DLL3 SCDO1
Provider product page for 11-10038

Antibody data

Product number
11-10038 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-Delta like 3 Antibody
Antibody type
Polyclonal
Description
Delta like 3 (DLL3) is a member of Delta/Serrate/Lag2 (DSL) ligands for Notch receptors and plays a role in Notch signaling. Out of Five DSL ligands, DLL3 is the most structurally divergent DSL ligand. DLL3 is expressed throughout the presomitic mesoderm and is localized to the rostral somatic compartments. Homozygous disruptions of Notch1 and DLL3 result in severe abnormalities in somitogenesis. Mutations in the human DLL3 homolog cause recessive skeletal abnormalities in spondylocostal dysostosis with a consistent pattern of abnormal segmentation.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant Delta
like 3 protein (amino acids 62-286)
was used as the immunogen for this
antibody.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
DLL3 protein structure - 11-10038 shown in red.