Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-10038-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-Delta like 3 Antibody
- Antibody type
- Polyclonal
- Description
- Delta like 3 (DLL3) is a member of Delta/Serrate/Lag2 (DSL) ligands for Notch receptors and plays a role in Notch signaling. Out of Five DSL ligands, DLL3 is the most structurally divergent DSL ligand. DLL3 is expressed throughout the presomitic mesoderm and is localized to the rostral somatic compartments. Homozygous disruptions of Notch1 and DLL3 result in severe abnormalities in somitogenesis. Mutations in the human DLL3 homolog cause recessive skeletal abnormalities in spondylocostal dysostosis with a consistent pattern of abnormal segmentation.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant Delta
like 3 protein (amino acids 62-286)
was used as the immunogen for this
antibody.- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Expression analysis of Delta like 3. Anti-Delta like 3 antibody (11-10038) was used at 2 µg/ml on A375 lysate.