Tissue expression
Cell line expression
Protein structure
PSMB7
Proteasome 20S subunit beta 7Z
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Jul 2012]
Top validated antibodies |
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NSJ Bioreagents | RQ7026 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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Proteintech Group | 14727-1-AP | 3 references | Polyclonal |
WB
EL
IHC
|
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Invitrogen Antibodies | PA5-30988 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Biorbyt | orb1145803 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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LSBio | LS-C392703 | Polyclonal |
WB
EL
IHC
|
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