DPABH-19234

TDG antibody from Creative Diagnostics
Western blot
Recommended by provider
ELISA
Recommended by provider
Immunocytochemistry
Recommended by provider
Immunoprecipitation
Recommended by provider
Immunohistochemistry
Recommended by provider
Chromatin Immunoprecipitation
Recommended by provider

Antibody data

Product number
DPABH-19234
Provider
Creative Diagnostics
Proper citation
Creative Diagnostics Cat#DPABH-19234, RRID:AB_2515034
Product name
Rabbit Anti-Human TDG Polyclonal antibody
Provider product page
Creative Diagnostics - DPABH-19234
Antibody type
Polyclonal
Description
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Vial size
50 uL
Provider Type Product Number
- No reagents -