DPABH-19234
TDG antibody from Creative Diagnostics
- Western blot
Recommended by provider
- ELISA
- Recommended by provider
- Immunocytochemistry
- Recommended by provider
- Immunoprecipitation
- Recommended by provider
- Immunohistochemistry
- Recommended by provider
- Chromatin Immunoprecipitation
- Recommended by provider
Antibody data
- Antibody Data
- Knockdown Reagents [0]
- References [0]
- Comments [0]
- Validations [0]
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- Product number
- DPABH-19234
- Provider
- Creative Diagnostics
- Proper citation
- Creative Diagnostics Cat#DPABH-19234, RRID:AB_2515034
- Product name
- Rabbit Anti-Human TDG Polyclonal antibody
- Provider product page
- Creative Diagnostics - DPABH-19234
- Antibody type
- Polyclonal
- Description
- The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50 uL
| Provider | Type | Product Number |
|---|---|---|
| - No reagents - | ||