10111-1-AP
antibody from Proteintech Group
Targeting: NUMBL
CAG3A, CTG3a, NUMB-R, NUMBLIKE, NUMBR, TNRC23
Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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Validation data
Reference
Comment
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- Product number
- 10111-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10111-1-AP, RRID:AB_2154440
- Product name
- NUMBL antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NUMBL antibody (Cat. #10111-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways.
Regulation of lung cancer metastasis by Klf4-Numb-like signaling.
Numb deletion in POMC-expressing cells impairs pituitary intermediate lobe cell adhesion, progenitor cell localization, and neuro-intermediate lobe boundary formation.
Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors.
Effects of testosterone supplementation on skeletal muscle fiber hypertrophy and satellite cells in community-dwelling older men.
Okubo Y, Ohtake F, Igarashi K, Yasuhiko Y, Hirabayashi Y, Saga Y, Kanno J
Development (Cambridge, England) 2021 Oct 1;148(19)
Development (Cambridge, England) 2021 Oct 1;148(19)
Regulation of lung cancer metastasis by Klf4-Numb-like signaling.
Vaira V, Faversani A, Martin NM, Garlick DS, Ferrero S, Nosotti M, Kissil JL, Bosari S, Altieri DC
Cancer research 2013 Apr 15;73(8):2695-705
Cancer research 2013 Apr 15;73(8):2695-705
Numb deletion in POMC-expressing cells impairs pituitary intermediate lobe cell adhesion, progenitor cell localization, and neuro-intermediate lobe boundary formation.
Moran TB, Goldberg LB, Serviss SL, Raetzman LT
Molecular endocrinology (Baltimore, Md.) 2011 Jan;25(1):117-27
Molecular endocrinology (Baltimore, Md.) 2011 Jan;25(1):117-27
Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors.
Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N
Nature neuroscience 2007 Jul;10(7):819-27
Nature neuroscience 2007 Jul;10(7):819-27
Effects of testosterone supplementation on skeletal muscle fiber hypertrophy and satellite cells in community-dwelling older men.
Sinha-Hikim I, Cornford M, Gaytan H, Lee ML, Bhasin S
The Journal of clinical endocrinology and metabolism 2006 Aug;91(8):3024-33
The Journal of clinical endocrinology and metabolism 2006 Aug;91(8):3024-33
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 10111-1-AP( NUMBLIKE Antibody) at dilution of 1:2000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using NUMBL antibody 10111-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-NUMBLIKE (IP:10111-1-AP, 3ug; Detection:10111-1-AP 1:1000) with HeLa cells lysate 1000ug.
- Sample type
- cell line