Antibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 657803 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#657803, RRID:AB_2562754
- Product name
- PE anti-Lin28A
- Antibody type
- Monoclonal
- Antigen
- Recombinant human Lin28A from E. coli
- Description
- LIN28A is a highly conserved RNA-binding protein and reprogramming factor that plays important roles in development, self-renewal of stem cells, glucose metabolism and tumorigenesis. Lin28A modulates not only miRNAs, particularly the let-7 family miRNAs, but also the translation of mRNAs that are important for cell growth and metabolism. LIN28A/B has been observed to be overexpressed in a wide range of solid tumors and hematological malignancies, and has emerged as a new therapeutic target candidate for cancer.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Antibody clone number
- 14E6-4E6
- Vial size
- 25 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human teratocarcinoma cell line, NCCIT was fixed and permeabilized with Nuclear Factor Fixation and Permeabilization Buffer Set (Cat. No. 422601), and then stained with anti-human Lin28 (clone 14E6-4E6) PE (filled histogram) or mouse IgG2a, κ PE isotype control (open histogram).
- Conjugate
- Yellow dye