Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN951782 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 0.1 mg
Submitted references OPRM1 and CYP2B6 gene variants as risk factors in methadone-related deaths.
Population pharmacokinetic-pharmacogenetic study of nevirapine in HIV-infected Cambodian patients.
The convergence of therapeutic drug monitoring and pharmacogenetic testing to optimize efavirenz therapy.
An approach based on a genome-wide association study reveals candidate loci for narcolepsy.
Bunten H, Liang WJ, Pounder DJ, Seneviratne C, Osselton D
Clinical pharmacology and therapeutics 2010 Sep;88(3):383-9
Clinical pharmacology and therapeutics 2010 Sep;88(3):383-9
Population pharmacokinetic-pharmacogenetic study of nevirapine in HIV-infected Cambodian patients.
Chou M, Bertrand J, Segeral O, Verstuyft C, Borand L, Comets E, Le Tiec C, Becquemont L, Ouk V, Mentre F, Taburet AM
Antimicrobial agents and chemotherapy 2010 Oct;54(10):4432-9
Antimicrobial agents and chemotherapy 2010 Oct;54(10):4432-9
The convergence of therapeutic drug monitoring and pharmacogenetic testing to optimize efavirenz therapy.
Cabrera Figueroa S, Fernández de Gatta M, Hernández García L, Domínguez-Gil Hurlé A, Bustos Bernal C, Sepúlveda Correa R, García Sánchez MJ
Therapeutic drug monitoring 2010 Oct;32(5):579-85
Therapeutic drug monitoring 2010 Oct;32(5):579-85
An approach based on a genome-wide association study reveals candidate loci for narcolepsy.
Shimada M, Miyagawa T, Kawashima M, Tanaka S, Honda Y, Honda M, Tokunaga K
Human genetics 2010 Oct;128(4):433-41
Human genetics 2010 Oct;128(4):433-41
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of CYP2B6 Antibody (Center) Cat.-No AP51170PU-N in 293 cell line lysates (35ug/lane). This demonstrates the CYP2B6 antibody detected the CYP2B6 protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Confocal immunofluorescent analysis of CYP2B6 Antibody (Center) Cat.-No AP51170PU-N with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Formalin fixed, paraffin embedded human hepatocarcinoma stained with CYP2B6 Antibody (Center) Cat.-No AP51170PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of CYP2B6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.