316904

antibody from BioLegend
Targeting: TNFRSF13C BAFFR, CD268
Provider product page for 316904

Antibody data

Product number
316904 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#316904, RRID:AB_528981
Product name
FITC anti-human CD268 (BAFF-R, BAFFR)
Antibody type
Monoclonal
Antigen
BAFF-R-L1.2 transfectants
Description
B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-κ B activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-κ B activation.
Reactivity
Human
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
TNFRSF13C protein structure - 316904 shown in red.