Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- PAB4388 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4388, RRID:AB_1579646
- Product name
- RCAN2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of RCAN2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling.
A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2).
DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways.
Rothermel B, Vega RB, Yang J, Wu H, Bassel-Duby R, Williams RS
The Journal of biological chemistry 2000 Mar 24;275(12):8719-25
The Journal of biological chemistry 2000 Mar 24;275(12):8719-25
A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2).
Strippoli P, Lenzi L, Petrini M, Carinci P, Zannotti M
Genomics 2000 Mar 15;64(3):252-63
Genomics 2000 Mar 15;64(3):252-63
DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways.
Fuentes JJ, Genescà L, Kingsbury TJ, Cunningham KW, Pérez-Riba M, Estivill X, de la Luna S
Human molecular genetics 2000 Jul 1;9(11):1681-90
Human molecular genetics 2000 Jul 1;9(11):1681-90
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of NCI-H460 cell lysate (35 ug/lane) with RCAN2 polyclonal antibody (Cat # PAB4388).
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of mouse heart tissue lysate (35 ug/lane) with RCAN2 polyclonal antibody (Cat # PAB4388).