Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- MB0143 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- IL18BP monoclonal antibody
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length Human IL18BP.
- Description
- The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine,IL18. It binds IL18,prevents the binding of IL18 to its receptor,and thus inhibits IL18-induced IFN-gamma production,resulting in reduced T-helper type 1 immune responses.This protein is constitutively expressed and secreted in mononuclear cells.Elevated level of this protein is detected in the intestinal tissues of patients with Crohn¡És disease.Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Reactivity
- Human
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot detection of IL18BP antibody in CHO-K1 cells transfected by IL18BP-PDGFR fusion protein and K562 cell lysates using IL18BP antibody (1:400-1:1000 diluted) .