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- Product number
- DM1207 - Provider product page
- Provider
- OriGene
- Product name
- CEACAM7 mouse monoclonal antibody, clone BAC2, Purified
- Antibody type
- Monoclonal
- Description
- CEACAM7 mouse monoclonal antibody, clone BAC2, Purified
- Host
- Mouse
- Conjugate
- Unconjugated
- Epitope
- CEACAM7
- Isotype
- IgG
- Antibody clone number
- BAC2
- Vial size
- 100 µg
- Concentration
- 1.0 mg/ml
Submitted references Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas.
Schölzel S, Zimmermann W, Schwarzkopf G, Grunert F, Rogaczewski B, Thompson J
The American journal of pathology 2000 Feb;156(2):595-605
The American journal of pathology 2000 Feb;156(2):595-605
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Supportive validation
- Submitted by
- OriGene (provider)
- Main image
- Experimental details
- Figure 2. Members of the CEACAM family were expressed on BOSC cells after transient transfection withexpression vectors containing either the cDNA of CEACAM1, 5, 6, 7, 8 or a recombinant trans-membrane-anchored PSG1 fusion protein. Recognition of CEACAM3, CEACAM4 and PSG1 was tested on stably transfected HeLa (CEACAM3, PSG) and CHO cells (CEACAM4), respectively. Expression of the con-structs was confirmed with monoclonal antibodies known to recognize the corresponding proteins (CEACAM1, 3, 4, 5 and 6: D14HD11; CEACAM7: CAC2; CEACAM8: TET2; PSG: Brified BAC2 was tested on all CEACAM transfectants. A positive signal was only obtained with CEACAM7 expressing cells (Red curves).
- Validation comment
- FC
- Submitted by
- OriGene (provider)
- Main image
- Experimental details
- Figure 1. FACS analysis of BOSC23 cells using BAC2 . BOSC23 cells were transiently transfected with an expression vectorencoding either CEACAM7 (Red curve) or an irrelevant protein (control transfectant). Binding of BAC2 was detected with a PE conjugated secondary antibody. A positive signal was obtained only with CEACAM7 transfected cells.
- Validation comment
- FC
