Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 19066-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19066-1-AP, RRID:AB_10667008
- Product name
- CRISP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CRISP2 antibody (Cat. #19066-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Characterization of different oligomeric forms of CRISP2 in the perinuclear theca versus the fibrous tail structures of boar spermatozoa†.
Functional redundancy and compensation: Deletion of multiple murine Crisp genes reveals their essential role for male fertility.
MicroRNA-27a-mediated repression of cysteine-rich secretory protein 2 translation in asthenoteratozoospermic patients.
PNLDC1 is essential for piRNA 3' end trimming and transposon silencing during spermatogenesis in mice.
Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: implications for fertility disorders.
The expression of cysteine-rich secretory protein 2 (CRISP2) and its specific regulator miR-27b in the spermatozoa of patients with asthenozoospermia.
DAZAP1 regulates the splicing of Crem, Crisp2 and Pot1a transcripts.
Zhang M, Bromfield EG, Veenendaal T, Klumperman J, Helms JB, Gadella BM
Biology of reproduction 2021 Nov 15;105(5):1160-1170
Biology of reproduction 2021 Nov 15;105(5):1160-1170
Functional redundancy and compensation: Deletion of multiple murine Crisp genes reveals their essential role for male fertility.
Curci L, Brukman NG, Weigel Muñoz M, Rojo D, Carvajal G, Sulzyk V, Gonzalez SN, Rubinstein M, Da Ros VG, Cuasnicú PS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):15718-15733
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):15718-15733
MicroRNA-27a-mediated repression of cysteine-rich secretory protein 2 translation in asthenoteratozoospermic patients.
Zhou JH, Zhou QZ, Yang JK, Lyu XM, Bian J, Guo WB, Chen ZJ, Xia M, Xia H, Qi T, Li X, Liu CD
Asian journal of andrology 2017 Sep-Oct;19(5):591-595
Asian journal of andrology 2017 Sep-Oct;19(5):591-595
PNLDC1 is essential for piRNA 3' end trimming and transposon silencing during spermatogenesis in mice.
Ding D, Liu J, Dong K, Midic U, Hess RA, Xie H, Demireva EY, Chen C
Nature communications 2017 Oct 10;8(1):819
Nature communications 2017 Oct 10;8(1):819
Fertilization defects in sperm from Cysteine-rich secretory protein 2 (Crisp2) knockout mice: implications for fertility disorders.
Brukman NG, Miyata H, Torres P, Lombardo D, Caramelo JJ, Ikawa M, Da Ros VG, Cuasnicú PS
Molecular human reproduction 2016 Apr;22(4):240-51
Molecular human reproduction 2016 Apr;22(4):240-51
The expression of cysteine-rich secretory protein 2 (CRISP2) and its specific regulator miR-27b in the spermatozoa of patients with asthenozoospermia.
Zhou JH, Zhou QZ, Lyu XM, Zhu T, Chen ZJ, Chen MK, Xia H, Wang CY, Qi T, Li X, Liu CD
Biology of reproduction 2015 Jan;92(1):28
Biology of reproduction 2015 Jan;92(1):28
DAZAP1 regulates the splicing of Crem, Crisp2 and Pot1a transcripts.
Chen HY, Yu YH, Yen PH
Nucleic acids research 2013 Nov;41(21):9858-69
Nucleic acids research 2013 Nov;41(21):9858-69
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 19066-1-AP(CRISP2 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 19066-1-AP(CRISP2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CRISP2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CRISP2. This antibody recognizes human, mouse antigen. The CRISP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.