APR04235G

antibody from Leading Biology

Targeting: CRISP1 AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP

Western blot (Recommended by provider)

Antibody Data

Product number

APR04235G

Provider

Leading Biology

Product name

CRISP1 Antibody (C-term)

Antibody type

Polyclonal

Description

Fertilization consists of a sequence of specific cell-cellinteractions culminating in the fusion of the sperm and egg plasmamembranes. Recognition, binding, and fusion occur through theinteraction of complementary molecules that are localized tospecific domains of the sperm and egg plasma membranes. In thesperm, the postacrosomal region or equatorial segment is involvedin sperm-egg plasma membrane fusion. The protein encoded by thisgene is a member of the cysteine-rich secretory protein (CRISP)family. This protein is expressed in the epididymis, is secretedinto the epididymal lumen, and binds to the postacrosomal region ofthe sperm head where it plays a role at fertilization in sperm-eggfusion through complementary sites localized on the egg surface.Two isoforms are encoded by transcript variants of this gene.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.