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Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Western blot [2]
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- Product number
- NB300-113 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB300-113, RRID:AB_2108990
- Product name
- Rabbit Polyclonal Glycine Receptor Alpha 1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specific for the ~48 kDa alpha1- and alpha2-subunits of the glycine receptor in Western blots of rat spinal cord and brain stem and in cell extracts. Does not recognize other glycine receptor subunits.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.2 mg
- Concentration
- LYOPH
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABA(A) receptor isoform in a cell model of hyperekplexia.
Involvement of glycine receptor α1 subunits in cannabinoid-induced analgesia.
Zou G, Xia J, Han Q, Liu D, Xiong W
The Journal of biological chemistry 2020 Jan 3;295(1):138-145
The Journal of biological chemistry 2020 Jan 3;295(1):138-145
Involvement of glycine receptor α1 subunits in cannabinoid-induced analgesia.
Lu J, Fan S, Zou G, Hou Y, Pan T, Guo W, Yao L, Du F, Homanics GE, Liu D, Zhang L, Xiong W
Neuropharmacology 2018 May 1;133:224-232
Neuropharmacology 2018 May 1;133:224-232
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Glycine Receptor Alpha 1 Antibody [NB300-113] - Rat spinal cord showing specific immunolabeling of the ~48k a1- and a2-subunits of the glycine receptor. The labeling was absent from a Rat hippocampal (hipp) lysate as the glycine receptor is not expressed in the hippocampus.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Glycine Receptor Alpha 1 Antibody [NB300-113] - Western blot of 10 ug of rat spinal cord. The antibody is specific for the ~48 kDa a1- and a2-subunitsof the glycine receptor.
