Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations [0]
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- Product number
- 26312-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- MCU/CCDC109A antibody
- Antibody type
- Polyclonal
- Description
- MCU/CCDC109A antibody (Cat. #26312-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TOM40 mediates the effect of TSPO on postpartum depression partially through regulating calcium homeostasis in microglia.
CGI1746 targets σ(1)R to modulate ferroptosis through mitochondria-associated membranes.
SERCA2 dysfunction triggers hypertension by interrupting mitochondrial homeostasis and provoking oxidative stress.
Puerarin Ameliorated PCOS through Preventing Mitochondrial Dysfunction Dependent on the Maintenance of Intracellular Calcium Homeostasis.
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
RNA Interference against ATP as a Gene Therapy Approach for Prostate Cancer.
Electro-metabolic coupling in multi-chambered vascularized human cardiac organoids.
Modulation of oxidized low-density lipoprotein-affected macrophage efferocytosis by mitochondrial calcium uniporter in a murine model.
EFHD1, a novel mitochondrial regulator of tumor metastasis in clear cell renal cell carcinoma.
Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts.
SMDT1 variants impair EMRE-mediated mitochondrial calcium uptake in patients with muscle involvement.
A mitochondrial inside-out iron-calcium signal reveals drug targets for Parkinson's disease.
Mechanism of aconitine mediated neuronal apoptosis induced by mitochondrial calcium overload caused by MCU.
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
CD137 Signal Mediates Cardiac Ischemia-Reperfusion Injury by Regulating the Necrosis of Cardiomyocytes.
Ca(2+)-mediated mitochondrial inner membrane permeabilization induces cell death independently of Bax and Bak.
Effects of MICU1-Mediated Mitochondrial Calcium Uptake on Energy Metabolism and Quality of Vitrified-Thawed Mouse Metaphase II Oocytes.
MICU3 regulates mitochondrial Ca(2+)-dependent antioxidant response in skeletal muscle aging.
PINK1 contained in huMSC-derived exosomes prevents cardiomyocyte mitochondrial calcium overload in sepsis via recovery of mitochondrial Ca(2+) efflux.
Sulforaphane Balances Ca(2+) Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Zhai DS, Wang XS, Yang L, Jiang YL, Jin YC, Yan YX, Song DK, Zhang K, Han ZK, Liu MY, Wu YM, Ma X, Qi JY, Yang F, Tian F, Li XB, Liu SB
Journal of affective disorders 2024 Mar 1;348:283-296
Journal of affective disorders 2024 Mar 1;348:283-296
CGI1746 targets σ(1)R to modulate ferroptosis through mitochondria-associated membranes.
Zhang Z, Zhou H, Gu W, Wei Y, Mou S, Wang Y, Zhang J, Zhong Q
Nature chemical biology 2024 Jun;20(6):699-709
Nature chemical biology 2024 Jun;20(6):699-709
SERCA2 dysfunction triggers hypertension by interrupting mitochondrial homeostasis and provoking oxidative stress.
Wang Y, Wang M, Su H, Song J, Ren M, Hu P, Liu G, Tong X
Free radical biology & medicine 2024 Feb 20;212:284-294
Free radical biology & medicine 2024 Feb 20;212:284-294
Puerarin Ameliorated PCOS through Preventing Mitochondrial Dysfunction Dependent on the Maintenance of Intracellular Calcium Homeostasis.
Wang YS, Li BY, Xing YF, Huang JC, Chen ZS, Yue L, Zou YG, Guo B
Journal of agricultural and food chemistry 2024 Feb 14;72(6):2963-2976
Journal of agricultural and food chemistry 2024 Feb 14;72(6):2963-2976
TDCPP and TiO(2) NPs aggregates synergistically induce SH-SY5Y cell neurotoxicity by excessive mitochondrial fission and mitophagy inhibition.
Wang L, Wang B, Zhang X, Yang Z, Zhang X, Gong H, Song Y, Zhang K, Sun M
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
Environmental pollution (Barking, Essex : 1987) 2024 Apr 15;347:123740
RNA Interference against ATP as a Gene Therapy Approach for Prostate Cancer.
Chen S, Ma J, Xiao Y, Zhou D, He P, Chen Y, Zheng X, Lin H, Qiu F, Yuan Y, Zhong J, Li X, Pan X, Fang Z, Wang C
Molecular pharmaceutics 2023 Oct 2;20(10):5214-5225
Molecular pharmaceutics 2023 Oct 2;20(10):5214-5225
Electro-metabolic coupling in multi-chambered vascularized human cardiac organoids.
Ghosheh M, Ehrlich A, Ioannidis K, Ayyash M, Goldfracht I, Cohen M, Fischer A, Mintz Y, Gepstein L, Nahmias Y
Nature biomedical engineering 2023 Nov;7(11):1493-1513
Nature biomedical engineering 2023 Nov;7(11):1493-1513
Modulation of oxidized low-density lipoprotein-affected macrophage efferocytosis by mitochondrial calcium uniporter in a murine model.
Lu N, Zhu JF, Lv HF, Zhang HP, Wang PL, Yang JJ, Wang XW
Immunology letters 2023 Nov;263:14-24
Immunology letters 2023 Nov;263:14-24
EFHD1, a novel mitochondrial regulator of tumor metastasis in clear cell renal cell carcinoma.
Meng K, Hu Y, Wang D, Li Y, Shi F, Lu J, Wang Y, Cao Y, Zhang CZ, He QY
Cancer science 2023 May;114(5):2029-2040
Cancer science 2023 May;114(5):2029-2040
Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts.
Zhang Y, Li JJ, Xu R, Wang XP, Zhao XY, Fang Y, Chen YP, Ma S, Di XH, Wu W, She G, Pang ZD, Wang YD, Zhang X, Xie W, Deng XL, Du XJ, Zhang Y
Redox biology 2023 Dec;68:102944
Redox biology 2023 Dec;68:102944
SMDT1 variants impair EMRE-mediated mitochondrial calcium uptake in patients with muscle involvement.
Bulthuis EP, Adjobo-Hermans MJW, de Potter B, Hoogstraten S, Wezendonk LHT, Tutakhel OAZ, Wintjes LT, van den Heuvel B, Willems PHGM, Kamsteeg EJ, Gozalbo MER, Sallevelt SCEH, Koudijs SM, Nicolai J, de Bie CI, Hoogendijk JE, Koopman WJH, Rodenburg RJ
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166808
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166808
A mitochondrial inside-out iron-calcium signal reveals drug targets for Parkinson's disease.
Bharat V, Durairaj AS, Vanhauwaert R, Li L, Muir CM, Chandra S, Kwak CS, Le Guen Y, Nandakishore P, Hsieh CH, Rensi SE, Altman RB, Greicius MD, Feng L, Wang X
Cell reports 2023 Dec 26;42(12):113544
Cell reports 2023 Dec 26;42(12):113544
Mechanism of aconitine mediated neuronal apoptosis induced by mitochondrial calcium overload caused by MCU.
Jiang C, Shen J, Wang C, Huang Y, Wang L, Yang Y, Hu W, Li P, Wu H
Toxicology letters 2023 Aug 1;384:86-95
Toxicology letters 2023 Aug 1;384:86-95
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Geng J, Khaket TP, Pan J, Li W, Zhang Y, Ping Y, Cobos Sillero MI, Lu B
Developmental cell 2023 Apr 10;58(7):597-615.e10
Developmental cell 2023 Apr 10;58(7):597-615.e10
CD137 Signal Mediates Cardiac Ischemia-Reperfusion Injury by Regulating the Necrosis of Cardiomyocytes.
Xu Y, Chen R, Yan J, Zang G, Shao C, Wang Z
Journal of cardiovascular translational research 2022 Oct;15(5):1163-1175
Journal of cardiovascular translational research 2022 Oct;15(5):1163-1175
Ca(2+)-mediated mitochondrial inner membrane permeabilization induces cell death independently of Bax and Bak.
Quarato G, Llambi F, Guy CS, Min J, Actis M, Sun H, Narina S, Pruett-Miller SM, Peng J, Rankovic Z, Green DR
Cell death and differentiation 2022 Jul;29(7):1318-1334
Cell death and differentiation 2022 Jul;29(7):1318-1334
Effects of MICU1-Mediated Mitochondrial Calcium Uptake on Energy Metabolism and Quality of Vitrified-Thawed Mouse Metaphase II Oocytes.
Lan T, Zhang K, Lin F, He Q, Wu S, Xu Z, Zhang Y, Quan F
International journal of molecular sciences 2022 Aug 3;23(15)
International journal of molecular sciences 2022 Aug 3;23(15)
MICU3 regulates mitochondrial Ca(2+)-dependent antioxidant response in skeletal muscle aging.
Yang YF, Yang W, Liao ZY, Wu YX, Fan Z, Guo A, Yu J, Chen QN, Wu JH, Zhou J, Xiao Q
Cell death & disease 2021 Nov 29;12(12):1115
Cell death & disease 2021 Nov 29;12(12):1115
PINK1 contained in huMSC-derived exosomes prevents cardiomyocyte mitochondrial calcium overload in sepsis via recovery of mitochondrial Ca(2+) efflux.
Zhou Q, Xie M, Zhu J, Yi Q, Tan B, Li Y, Ye L, Zhang X, Zhang Y, Tian J, Xu H
Stem cell research & therapy 2021 May 6;12(1):269
Stem cell research & therapy 2021 May 6;12(1):269
Sulforaphane Balances Ca(2+) Homeostasis Injured by Excessive Fat via Mitochondria-Associated Membrane (MAM).
Tian S, Lei P, Zhang J, Sun Y, Li B, Shan Y
Molecular nutrition & food research 2021 Jul;65(14):e2001076
Molecular nutrition & food research 2021 Jul;65(14):e2001076
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Zhang C, Nie P, Zhou C, Hu Y, Duan S, Gu M, Jiang D, Wang Y, Deng Z, Chen J, Chen S, Wang L
Cell death & disease 2021 Feb 24;12(2):209
Cell death & disease 2021 Feb 24;12(2):209
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