Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 16015-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16015-1-AP, RRID:AB_2145043
- Product name
- MMS19 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MMS19 antibody (Cat. #16015-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The cytosolic iron-sulfur cluster assembly (CIA) pathway is required for replication stress tolerance of cancer cells to Chk1 and ATR inhibitors.
Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.
The iron-sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation.
The iron-sulphur cluster in human DNA2 is required for all biochemical activities of DNA2.
Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis.
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis.
Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes.
Cytosolic HSC20 integrates de novo iron-sulfur cluster biogenesis with the CIAO1-mediated transfer to recipients.
Cytosolic Iron-Sulfur Assembly Is Evolutionarily Tuned by a Cancer-Amplified Ubiquitin Ligase.
Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue.
The CIA Targeting Complex Is Highly Regulated and Provides Two Distinct Binding Sites for Client Iron-Sulfur Proteins.
The Association of the Xeroderma Pigmentosum Group D DNA Helicase (XPD) with Transcription Factor IIH Is Regulated by the Cytosolic Iron-Sulfur Cluster Assembly Pathway.
Methyl-methanesulfonate sensitivity 19 expression is associated with metastasis and chemoradiotherapy response in esophageal cancer.
Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.
MicroRNA-31 modulates tumour sensitivity to radiation in oesophageal adenocarcinoma.
Redwood AB, Zhang X, Seth SB, Ge Z, Bindeman WE, Zhou X, Sinha VC, Heffernan TP, Piwnica-Worms H
NPJ breast cancer 2021 Dec 2;7(1):152
NPJ breast cancer 2021 Dec 2;7(1):152
Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.
Yang SW, Huang X, Lin W, Min J, Miller DJ, Mayasundari A, Rodrigues P, Griffith EC, Gee CT, Li L, Li W, Lee RE, Rankovic Z, Chen T, Potts PR
Nature communications 2020 Oct 1;11(1):4931
Nature communications 2020 Oct 1;11(1):4931
The iron-sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation.
Simon AK, Kummer S, Wild S, Lezaja A, Teloni F, Jozwiakowski SK, Altmeyer M, Gari K
Life science alliance 2020 Mar;3(3)
Life science alliance 2020 Mar;3(3)
The iron-sulphur cluster in human DNA2 is required for all biochemical activities of DNA2.
Mariotti L, Wild S, Brunoldi G, Piceni A, Ceppi I, Kummer S, Lutz RE, Cejka P, Gari K
Communications biology 2020 Jun 23;3(1):322
Communications biology 2020 Jun 23;3(1):322
Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis.
Maio N, Kim KS, Holmes-Hampton G, Singh A, Rouault TA
Haematologica 2019 Sep;104(9):1756-1767
Haematologica 2019 Sep;104(9):1756-1767
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis.
Ast T, Meisel JD, Patra S, Wang H, Grange RMH, Kim SH, Calvo SE, Orefice LL, Nagashima F, Ichinose F, Zapol WM, Ruvkun G, Barondeau DP, Mootha VK
Cell 2019 May 30;177(6):1507-1521.e16
Cell 2019 May 30;177(6):1507-1521.e16
Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes.
Paul BT, Tesfay L, Winkler CR, Torti FM, Torti SV
Scientific reports 2019 Dec 23;9(1):19634
Scientific reports 2019 Dec 23;9(1):19634
Cytosolic HSC20 integrates de novo iron-sulfur cluster biogenesis with the CIAO1-mediated transfer to recipients.
Kim KS, Maio N, Singh A, Rouault TA
Human molecular genetics 2018 Mar 1;27(5):837-852
Human molecular genetics 2018 Mar 1;27(5):837-852
Cytosolic Iron-Sulfur Assembly Is Evolutionarily Tuned by a Cancer-Amplified Ubiquitin Ligase.
Weon JL, Yang SW, Potts PR
Molecular cell 2018 Jan 4;69(1):113-125.e6
Molecular cell 2018 Jan 4;69(1):113-125.e6
Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue.
Palmer CJ, Bruckner RJ, Paulo JA, Kazak L, Long JZ, Mina AI, Deng Z, LeClair KB, Hall JA, Hong S, Zushin PH, Smith KL, Gygi SP, Hagen S, Cohen DE, Banks AS
Molecular metabolism 2017 Oct;6(10):1212-1225
Molecular metabolism 2017 Oct;6(10):1212-1225
The CIA Targeting Complex Is Highly Regulated and Provides Two Distinct Binding Sites for Client Iron-Sulfur Proteins.
Odermatt DC, Gari K
Cell reports 2017 Feb 7;18(6):1434-1443
Cell reports 2017 Feb 7;18(6):1434-1443
The Association of the Xeroderma Pigmentosum Group D DNA Helicase (XPD) with Transcription Factor IIH Is Regulated by the Cytosolic Iron-Sulfur Cluster Assembly Pathway.
Vashisht AA, Yu CC, Sharma T, Ro K, Wohlschlegel JA
The Journal of biological chemistry 2015 May 29;290(22):14218-25
The Journal of biological chemistry 2015 May 29;290(22):14218-25
Methyl-methanesulfonate sensitivity 19 expression is associated with metastasis and chemoradiotherapy response in esophageal cancer.
Zhang JL, Wang HY, Yang Q, Lin SY, Luo GY, Zhang R, Xu GL
World journal of gastroenterology 2015 Apr 14;21(14):4240-7
World journal of gastroenterology 2015 Apr 14;21(14):4240-7
Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins.
Stehling O, Mascarenhas J, Vashisht AA, Sheftel AD, Niggemeyer B, Rösser R, Pierik AJ, Wohlschlegel JA, Lill R
Cell metabolism 2013 Aug 6;18(2):187-98
Cell metabolism 2013 Aug 6;18(2):187-98
MicroRNA-31 modulates tumour sensitivity to radiation in oesophageal adenocarcinoma.
Lynam-Lennon N, Reynolds JV, Marignol L, Sheils OM, Pidgeon GP, Maher SG
Journal of molecular medicine (Berlin, Germany) 2012 Dec;90(12):1449-58
Journal of molecular medicine (Berlin, Germany) 2012 Dec;90(12):1449-58
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MMS19 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MMS19. This antibody recognizes human, mouse, rat antigen. The MMS19 antibody has been validated for the following applications: ELISA, WB analysis.