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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 66049-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66049-1-Ig, RRID:AB_11041708
- Product name
- MMS19 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated MMS19 antibody (Cat. #66049-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2H6D8
- Vial size
- 20ul, 150ul
Submitted references An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis.
MMS19 as a potential predictive marker of adjuvant chemotherapy benefit in resected non-small cell lung cancer.
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.
Mayank AK, Pandey V, Vashisht AA, Barshop WD, Rayatpisheh S, Sharma T, Haque T, Powers DN, Wohlschlegel JA
Molecular cell 2019 Jul 25;75(2):382-393.e5
Molecular cell 2019 Jul 25;75(2):382-393.e5
MMS19 as a potential predictive marker of adjuvant chemotherapy benefit in resected non-small cell lung cancer.
Adam J, Sourisseau T, Olaussen KA, Robin A, Zhu CQ, Templier A, Civet A, Girard P, Lazar V, Validire P, Tsao MS, Soria JC, Besse B
Cancer biomarkers : section A of Disease markers 2016 Sep 26;17(3):323-333
Cancer biomarkers : section A of Disease markers 2016 Sep 26;17(3):323-333
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.
Stehling O, Vashisht AA, Mascarenhas J, Jonsson ZO, Sharma T, Netz DJ, Pierik AJ, Wohlschlegel JA, Lill R
Science (New York, N.Y.) 2012 Jul 13;337(6091):195-9
Science (New York, N.Y.) 2012 Jul 13;337(6091):195-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 66049-1-Ig(MMS19 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using MMS19 antibody 66049-1-lg at 1:50 dilution and Rhodamine-labeled goat anti-mouse IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 66049-1-Ig(MMS19 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
