BS7905

antibody from Bioworld Technology, Inc
Targeting: NPRL2 NPR2, NPR2L, TUSC4
Provider product page for BS7905
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7905 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TUSC4 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TUSC4.
Description
NPRL2, also known as TUSC4 (tumor suppressor candidate 4), is a 380 amino acid protein that contains a bipartite nuclear localization signal and a granulin protein-binding domain. It is highly expressed in skeletal muscle, followed by brain, liver and pancreas, with lower expression in lung, kidney, placenta and heart. NPRL2 is also expressed in most lung cancer cell lines and may be involved in tumor suppression. NPRL2 may play a role in mismatch repair, cell cycle checkpoint signaling and activation of apoptotic pathways. It may also enhance the therapeutic efficacy of chemotherapy drugs such as cis-platin by resensitizing patients resistant to cisplatin treatment. The gene encoding NPRL2 is conserved between species and is expressed as two isoforms due to alternative splicing events.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NPRL2 protein structure - BS7905 shown in red.