BS3271

antibody from Bioworld Technology, Inc
Targeting: ABCD1 adrenoleukodystrophy, ALD, ALDP, AMN
Provider product page for BS3271

Antibody data

Product number
BS3271 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3271, RRID:AB_1662128
Product name
ABCD1 (D575) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 550-600 of Human ABCD1.
Description
The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1ÿ4 that are known to be present in the human peroxisome membrane. All four proteins are ABC half-transporters, which dimerize to form an active transporter. A mutation in the ABCD1 causes X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage. ABCD2 in mouse, is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD. The peroxisomal membrane comprises 2 quantitatively major proteins, PMP22 and ABCD3. ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors. ABCD4 localizes to peroxisomes.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ABCD1 protein structure - BS3271 shown in red.