Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR04101G - Provider product page
- Provider
- Leading Biology
- Product name
- YTHD2 Antibody (C-term)
- Antibody type
- Polyclonal
- Description
- YTHDF2 is a member of the YTH (YT521-B homology)superfamily containing YTH domain. The YTH domain is typical forthe eukaryotes and is particularly abundant in plants. The YTHdomain is usually located in the middle of the protein sequence andmay function in binding to RNA. In addition to a YTH domain, thisprotein has a proline rich region which may be involved in signaltransduction. An Alu-rich domain has been identified in one of theintrons of this gene, which is thought to be associated with humanlongevity. In addition, reciprocal translocations between this geneand the Runx1 (AML1) gene on chromosme 21 has been observed inpatients with acute myeloid leukemia. This gene was initiallymapped to chromosome 14, which was later turned out to be apseudogene.
- Reactivity
- Human
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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