Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- AF807 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal uPAR Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human uPAR in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mouse uPAR is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion.
Modification of kidney barrier function by the urokinase receptor.
Ang II-stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice.
Pitavastatin attenuates the PDGF-induced LR11/uPA receptor-mediated migration of smooth muscle cells.
Annis MG, Ouellet V, Rennhack JP, L'Esperance S, Rancourt C, Mes-Masson AM, Andrechek ER, Siegel PM
Breast cancer research : BCR 2018 Jan 30;20(1):9
Breast cancer research : BCR 2018 Jan 30;20(1):9
Modification of kidney barrier function by the urokinase receptor.
Wei C, Möller CC, Altintas MM, Li J, Schwarz K, Zacchigna S, Xie L, Henger A, Schmid H, Rastaldi MP, Cowan P, Kretzler M, Parrilla R, Bendayan M, Gupta V, Nikolic B, Kalluri R, Carmeliet P, Mundel P, Reiser J
Nature medicine 2008 Jan;14(1):55-63
Nature medicine 2008 Jan;14(1):55-63
Ang II-stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice.
Jiang M, Bujo H, Ohwaki K, Unoki H, Yamazaki H, Kanaki T, Shibasaki M, Azuma K, Harigaya K, Schneider WJ, Saito Y
The Journal of clinical investigation 2008 Aug;118(8):2733-46
The Journal of clinical investigation 2008 Aug;118(8):2733-46
Pitavastatin attenuates the PDGF-induced LR11/uPA receptor-mediated migration of smooth muscle cells.
Jiang M, Bujo H, Zhu Y, Yamazaki H, Hirayama S, Kanaki T, Shibasaki M, Takahashi K, Schneider WJ, Saito Y
Biochemical and biophysical research communications 2006 Oct 6;348(4):1367-77
Biochemical and biophysical research communications 2006 Oct 6;348(4):1367-77
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human uPAR by Western Blot. Detection of Human uPAR by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- uPAR in Human Lung Cancer Tissue. uPAR in Human Lung Cancer Tissue.