Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- MAB807-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human uPAR Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human uPAR in direct ELISAs and Western blots. When used in a sandwich ELISA in combination with the biotinylated anti-human uPAR detection antibody (Catalog # BAF807), no significant cross-reactivity was observed with recombinant mouse uPAR.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
Q03405
- Isotype
- IgG
- Antibody clone number
- 62022
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells.
The Periodontal Pathogen Porphyromonas gingivalis Preferentially Interacts with Oral Epithelial Cells in S Phase of the Cell Cycle.
Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion.
Intracellular modifiers of integrin alpha 6p production in aggressive prostate and breast cancer cell lines.
Urinary soluble urokinase receptor levels are elevated and pathogenic in patients with primary focal segmental glomerulosclerosis.
Plasmin cleavage of von Willebrand factor as an emergency bypass for ADAMTS13 deficiency in thrombotic microangiopathy.
Activation of the plasma kallikrein-kinin system on human lung epithelial cells.
AP-1-controlled hepatocyte growth factor activation promotes keratinocyte migration via CEACAM1 and urokinase plasminogen activator/urokinase plasminogen receptor.
Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine.
Development and validation of sandwich ELISA microarrays with minimal assay interference.
Urokinase-type plasminogen activator modulates airway eosinophil adhesion in asthma.
LDL-receptor-related protein regulates beta2-integrin-mediated leukocyte adhesion.
van Veen M, Matas-Rico E, van de Wetering K, Leyton-Puig D, Kedziora KM, De Lorenzi V, Stijf-Bultsma Y, van den Broek B, Jalink K, Sidenius N, Perrakis A, Moolenaar WH
eLife 2017 Aug 29;6
eLife 2017 Aug 29;6
The Periodontal Pathogen Porphyromonas gingivalis Preferentially Interacts with Oral Epithelial Cells in S Phase of the Cell Cycle.
Al-Taweel FB, Douglas CWI, Whawell SA
Infection and immunity 2016 Jul;84(7):1966-1974
Infection and immunity 2016 Jul;84(7):1966-1974
Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion.
Gilder AS, Jones KA, Hu J, Wang L, Chen CC, Carter BS, Gonias SL
The Journal of biological chemistry 2015 Jun 12;290(24):14798-809
The Journal of biological chemistry 2015 Jun 12;290(24):14798-809
Intracellular modifiers of integrin alpha 6p production in aggressive prostate and breast cancer cell lines.
Kacsinta AD, Rubenstein CS, Sroka IC, Pawar S, Gard JM, Nagle RB, Cress AE
Biochemical and biophysical research communications 2014 Nov 14;454(2):335-40
Biochemical and biophysical research communications 2014 Nov 14;454(2):335-40
Urinary soluble urokinase receptor levels are elevated and pathogenic in patients with primary focal segmental glomerulosclerosis.
Huang J, Liu G, Zhang YM, Cui Z, Wang F, Liu XJ, Chu R, Zhao MH
BMC medicine 2014 May 20;12:81
BMC medicine 2014 May 20;12:81
Plasmin cleavage of von Willebrand factor as an emergency bypass for ADAMTS13 deficiency in thrombotic microangiopathy.
Tersteeg C, de Maat S, De Meyer SF, Smeets MW, Barendrecht AD, Roest M, Pasterkamp G, Fijnheer R, Vanhoorelbeke K, de Groot PG, Maas C
Circulation 2014 Mar 25;129(12):1320-31
Circulation 2014 Mar 25;129(12):1320-31
Activation of the plasma kallikrein-kinin system on human lung epithelial cells.
Vergiliana JF, Asokananthan N, Stewart GA
Biological chemistry 2010 Sep;391(9):1067-77
Biological chemistry 2010 Sep;391(9):1067-77
AP-1-controlled hepatocyte growth factor activation promotes keratinocyte migration via CEACAM1 and urokinase plasminogen activator/urokinase plasminogen receptor.
Schnickmann S, Camacho-Trullio D, Bissinger M, Eils R, Angel P, Schirmacher P, Szabowski A, Breuhahn K
The Journal of investigative dermatology 2009 May;129(5):1140-8
The Journal of investigative dermatology 2009 May;129(5):1140-8
Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine.
Hu H, Kwun J, Aizenstein BD, Knechtle SJ
Transplantation 2009 Jun 27;87(12):1814-20
Transplantation 2009 Jun 27;87(12):1814-20
Development and validation of sandwich ELISA microarrays with minimal assay interference.
Gonzalez RM, Seurynck-Servoss SL, Crowley SA, Brown M, Omenn GS, Hayes DF, Zangar RC
Journal of proteome research 2008 Jun;7(6):2406-14
Journal of proteome research 2008 Jun;7(6):2406-14
Urokinase-type plasminogen activator modulates airway eosinophil adhesion in asthma.
Brooks AM, Bates ME, Vrtis RF, Jarjour NN, Bertics PJ, Sedgwick JB
American journal of respiratory cell and molecular biology 2006 Oct;35(4):503-11
American journal of respiratory cell and molecular biology 2006 Oct;35(4):503-11
LDL-receptor-related protein regulates beta2-integrin-mediated leukocyte adhesion.
Spijkers PP, da Costa Martins P, Westein E, Gahmberg CG, Zwaginga JJ, Lenting PJ
Blood 2005 Jan 1;105(1):170-7
Blood 2005 Jan 1;105(1):170-7
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of uPAR in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human uPAR Monoclonal Antibody (Catalog # MAB807, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B). View our protocol for Staining Membrane-associated Proteins.