APG00006G

antibody from Leading Biology

Targeting: PLAUR CD87, UPAR, URKR

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

APG00006G

Provider

Leading Biology

Product name

uPAR Antibody

Antibody type

Polyclonal

Description

uPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum β-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.

Reactivity

Human

Host

Goat

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.