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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 336902 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#336902, RRID:AB_2165470
- Product name
- Purified anti-human CD87
- Antibody type
- Monoclonal
- Antigen
- CD87
- Description
- CD87, known as urokinase plasminogen activator-receptor (uPAR), is a 36-68 kD single-chain glycophosphotidylinositol (GPI)-anchored glycoprotein. The extracellular region of CD87 consists of three homologous domains, D1, D2, and D3. Membrane-bound and soluble (D2D3) forms of uPAR have been reported. The membrane-bound CD87 is expressed on granulocytes, monocytes/macrophages, dendritic cells, fibroblasts, endothelial cells and keratinocytes. CD87 plays a role in cell adhesion and chemotaxis through binding to β1, β2 and β3 integrins. CD87-bound uPA converts plasminogen to plasmin.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human peripheral blood granulocytes stained with purified VIM5, followed by anti-mouse IgG FITC
- Conjugate
- Unconjugated
