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- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN500064 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Immunity-Related GTPase Family, Cinema (IRGC) (N-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- IRGC antibody was raised against a 13 amino acid peptide near the amino terminus of human IRGC.
- Description
- Peptide affinity chromtaography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Upregulation of immunity-related GTPase (IRG) proteins by TNF-alpha in murine astrocytes.
IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens.
Human IRGM induces autophagy to eliminate intracellular mycobacteria.
The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage.
Yamada K, Akimoto H, Ogawa Y, Kinumi T, Kamagata Y, Ohmiya Y
Biochemical and biophysical research communications 2009 May 1;382(2):434-9
Biochemical and biophysical research communications 2009 May 1;382(2):434-9
IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens.
Taylor GA
Cellular microbiology 2007 May;9(5):1099-107
Cellular microbiology 2007 May;9(5):1099-107
Human IRGM induces autophagy to eliminate intracellular mycobacteria.
Singh SB, Davis AS, Taylor GA, Deretic V
Science (New York, N.Y.) 2006 Sep 8;313(5792):1438-41
Science (New York, N.Y.) 2006 Sep 8;313(5792):1438-41
The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage.
Bekpen C, Hunn JP, Rohde C, Parvanova I, Guethlein L, Dunn DM, Glowalla E, Leptin M, Howard JC
Genome biology 2005;6(11):R92
Genome biology 2005;6(11):R92
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of IRGC in A20 cell lysate with AP30452PU-N at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of IRGC in A20 cells with AP30452PU-N at 5 ?g/ml.
