Tissue expression
Cell line expression
Protein structure
GLE1
GLE1 RNA export mediatorGLE1L, hGLE1, LCCS1
This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | PA5-117664 | Polyclonal |
WB
ICC
IP
IHC
OA
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Cusabio Biotech Co., Ltd | CSB-PA700651EA01HU | Polyclonal |
WB
EL
ICC
IP
IHC
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GeneTex | GTX31366 | Polyclonal |
WB
EL
ICC
IHC |
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Biorbyt | orb30685 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
Novus Biologicals | NBP1-76975 | Polyclonal |
WB
EL
ICC
IHC |
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