Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx032743 - Provider product page
- Provider
- Abbexa
- Product name
- 2'-5'-Oligoadenylate Synthetase 3 (OAS3) Antibody
- Antibody type
- Polyclonal
- Description
- OAS3 is an interferon inducible protein that belongs to the 2-5A synthetase family, may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. OAS3 synthesizes preferentially dimeric 2', 5'-oligoadenylate molecules. GTP can be an alternative substrate. OAS3 binds double-stranded RNA and polymerizes ATP into PPP (A2'P5'A) N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. The protein is present at high level in placenta trophoblast.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 80 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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