Tissue expression
Cell line expression
Protein structure
OAS2
2'-5'-oligoadenylate synthetase 2This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Proteintech Group | 19279-1-AP | 10 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 19279-1-AP | Polyclonal |
WB
ICC
IHC
OA |
||
NovoPro Bioscience Inc. | 113460 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
FineTest Biotech | FNab05951 | Polyclonal |
WB
EL
ICC
IP
IHC
|
||
Biorbyt | orb629500 | Polyclonal |
WB
EL
ICC
IP
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider