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LearnABIN1580436
antibody from antibodies-online
Targeting: MAPT
DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN1580436 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Microtubule-Associated Protein tau (MAPT) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- affinity purified antibody
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 2E9
- Vial size
- 100 μL
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term or -20°C long term.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Tau mutations in neurodegenerative diseases.
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders.
A century of Alzheimer's disease.
Distribution of Big tau in the central nervous system of the adult and developing rat.
Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system.
Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin.
A protein factor essential for microtubule assembly.
Wolfe MS
The Journal of biological chemistry 2009 Mar 6;284(10):6021-5
The Journal of biological chemistry 2009 Mar 6;284(10):6021-5
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders.
Ballatore C, Lee VM, Trojanowski JQ
Nature reviews. Neuroscience 2007 Sep;8(9):663-72
Nature reviews. Neuroscience 2007 Sep;8(9):663-72
A century of Alzheimer's disease.
Goedert M, Spillantini MG
Science (New York, N.Y.) 2006 Nov 3;314(5800):777-81
Science (New York, N.Y.) 2006 Nov 3;314(5800):777-81
Distribution of Big tau in the central nervous system of the adult and developing rat.
Boyne LJ, Tessler A, Murray M, Fischer I
The Journal of comparative neurology 1995 Jul 24;358(2):279-93
The Journal of comparative neurology 1995 Jul 24;358(2):279-93
Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system.
Goedert M, Spillantini MG, Crowther RA
Proceedings of the National Academy of Sciences of the United States of America 1992 Mar 1;89(5):1983-7
Proceedings of the National Academy of Sciences of the United States of America 1992 Mar 1;89(5):1983-7
Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin.
Cleveland DW, Hwo SY, Kirschner MW
Journal of molecular biology 1977 Oct 25;116(2):207-25
Journal of molecular biology 1977 Oct 25;116(2):207-25
A protein factor essential for microtubule assembly.
Weingarten MD, Lockwood AH, Hwo SY, Kirschner MW
Proceedings of the National Academy of Sciences of the United States of America 1975 May;72(5):1858-62
Proceedings of the National Academy of Sciences of the United States of America 1975 May;72(5):1858-62
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Blots of crude rat brain extract stained with ABIN1580436, revealing, as expected, multiple bands in the range 48-67kDa.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- We obtained Neuromics E18 hippocampal neurons and grew them for seven days following the Neuromics protocol. We fixed and immunostained with ABIN1580436 using our standard immunostaining protocol (green), ?s chicken antibody to ?-internexin (CPCA-Int, red) and for DNA (blue). ABIN1580436 stains the neuronal perikarya and process strongly, and does not stain non neuronal cells in these cultures. The ?-internexin antibody stains intermediate or 10nm filament bundles in the cytoplasm of these cells.
