10274-1-AP
antibody from Proteintech Group
Targeting: MAPT
DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau
Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- 10274-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10274-1-AP, RRID:AB_2139718
- Product name
- TAU antibody
- Antibody type
- Polyclonal
- Description
- TAU antibody (Cat. #10274-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: Implications for Alzheimer's disease.
Positive effect of Astragaloside IV on neurite outgrowth via talin-dependent integrin signaling and microfilament force.
The effects of antimony on Alzheimer's disease-like pathological changes in mice brain.
Laterality and region-specific tau phosphorylation correlate with PTSD-related behavioral traits in rats exposed to repetitive low-level blast.
Schizophrenia risk candidate EGR3 is a novel transcriptional regulator of RELN and regulates neurite outgrowth via the Reelin signal pathway in vitro.
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
NaoXinTong Capsule ameliorates memory deficit in APP/PS1 mice by regulating inflammatory cytokines.
Effects of the histone acetylase inhibitor C646 on growth and differentiation of adipose-derived stem cells.
Vitamin D Attenuates Alzheimer-like Pathology Induced by Okadaic Acid.
LongShengZhi Capsule Attenuates Alzheimer-Like Pathology in APP/PS1 Double Transgenic Mice by Reducing Neuronal Oxidative Stress and Inflammation.
Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells.
Toxoplasma gondii Chinese I genotype Wh6 strain infection induces tau phosphorylation via activating GSK3β and causes hippocampal neuron apoptosis.
TDZD-8 alleviates delayed neurological sequelae following acute carbon monoxide poisoning involving tau protein phosphorylation.
Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease.
Hypoxia induces HT-22 neuronal cell death via Orai1/CDK5 pathway-mediated Tau hyperphosphorylation.
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Talin promotes integrin activation accompanied by generation of tension in talin and an increase in osmotic pressure in neurite outgrowth.
Receptor-Mediated Field Effect Transistor Biosensor for Real-Time Monitoring of Glutamate Release from Primary Hippocampal Neurons.
The protective mechanism underlying phenylethanoid glycosides (PHG) actions on synaptic plasticity in rat Alzheimer's disease model induced by beta amyloid 1-42.
Dental pulp stem cells promote regeneration of damaged neuron cells on the cellular model of Alzheimer's disease.
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance.
Parkin deletion causes cerebral and systemic amyloidosis in human mutated tau over-expressing mice.
Zhang H, Zhang L, Zhou D, Li H, Xu Y
The Journal of comparative neurology 2021 Oct;529(15):3497-3512
The Journal of comparative neurology 2021 Oct;529(15):3497-3512
Positive effect of Astragaloside IV on neurite outgrowth via talin-dependent integrin signaling and microfilament force.
Wang Y, Zhou J, Tang C, Yu J, Zhu W, Guo J, Wang Y
Journal of cellular physiology 2021 Mar;236(3):2156-2168
Journal of cellular physiology 2021 Mar;236(3):2156-2168
The effects of antimony on Alzheimer's disease-like pathological changes in mice brain.
Xu S, Yang Z, Zhi Y, Yu S, Zhang T, Jiang J, Tang J, He H, Lu M, Wang X, Wu Q, Zhao X
The Science of the total environment 2021 Mar 15;760:143235
The Science of the total environment 2021 Mar 15;760:143235
Laterality and region-specific tau phosphorylation correlate with PTSD-related behavioral traits in rats exposed to repetitive low-level blast.
Perez Garcia G, De Gasperi R, Gama Sosa MA, Perez GM, Otero-Pagan A, Pryor D, Abutarboush R, Kawoos U, Hof PR, Dickstein DL, Cook DG, Gandy S, Ahlers ST, Elder GA
Acta neuropathologica communications 2021 Mar 1;9(1):33
Acta neuropathologica communications 2021 Mar 1;9(1):33
Schizophrenia risk candidate EGR3 is a novel transcriptional regulator of RELN and regulates neurite outgrowth via the Reelin signal pathway in vitro.
Nie F, Zhang Q, Ma J, Wang P, Gu R, Han J, Zhang R
Journal of neurochemistry 2021 Jun;157(6):1745-1758
Journal of neurochemistry 2021 Jun;157(6):1745-1758
The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro.
Ai J, Wang H, Chu P, Shopit A, Niu M, Ahmad N, Tesfaldet T, Wang FH, Fang JN, Li X, Tang SJ, Qing Ju Han, Han G, Peng J, Tang Z
Free radical biology & medicine 2021 Jan;162:181-190
Free radical biology & medicine 2021 Jan;162:181-190
NaoXinTong Capsule ameliorates memory deficit in APP/PS1 mice by regulating inflammatory cytokines.
Wang X, Yin Z, Cao P, Zheng S, Chen Y, Yu M, Liao C, Zhang Z, Duan Y, Han J, Zhang S, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110964
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jan;133:110964
Effects of the histone acetylase inhibitor C646 on growth and differentiation of adipose-derived stem cells.
Wang Z, Wang X, Bi M, Hu X, Wang Q, Liang H, Liu D
Cell cycle (Georgetown, Tex.) 2021 Feb;20(4):392-405
Cell cycle (Georgetown, Tex.) 2021 Feb;20(4):392-405
Vitamin D Attenuates Alzheimer-like Pathology Induced by Okadaic Acid.
Pan Y, Zhang Y, Liu N, Lu W, Yang J, Li Y, Liu Z, Wei Y, Lou Y, Kong J
ACS chemical neuroscience 2021 Apr 21;12(8):1343-1350
ACS chemical neuroscience 2021 Apr 21;12(8):1343-1350
LongShengZhi Capsule Attenuates Alzheimer-Like Pathology in APP/PS1 Double Transgenic Mice by Reducing Neuronal Oxidative Stress and Inflammation.
Yin Z, Wang X, Zheng S, Cao P, Chen Y, Yu M, Liao C, Zhang Z, Han J, Duan Y, Yang X, Zhang S
Frontiers in aging neuroscience 2020;12:582455
Frontiers in aging neuroscience 2020;12:582455
Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells.
Yin Z, Hua L, Chen L, Hu D, Li J, An Z, Tian T, Ning H, Ge Y
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104911
Toxicology in vitro : an international journal published in association with BIBRA 2020 Sep;67:104911
Toxoplasma gondii Chinese I genotype Wh6 strain infection induces tau phosphorylation via activating GSK3β and causes hippocampal neuron apoptosis.
Tao Q, Wang X, Liu L, Ji Y, Luo Q, Du J, Yu L, Shen J, Chu D
Acta tropica 2020 Oct;210:105560
Acta tropica 2020 Oct;210:105560
TDZD-8 alleviates delayed neurological sequelae following acute carbon monoxide poisoning involving tau protein phosphorylation.
Su C, Zhao N, Zou J, Yan X
Inhalation toxicology 2020 Feb;32(2):79-85
Inhalation toxicology 2020 Feb;32(2):79-85
Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease.
Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, Chan ER, Wang Q, Xu R, Flanagan ME, Pieper AA, Qi X
Science advances 2020 Dec;6(49)
Science advances 2020 Dec;6(49)
Hypoxia induces HT-22 neuronal cell death via Orai1/CDK5 pathway-mediated Tau hyperphosphorylation.
Fang B, Zhao Q, Ling W, Zhang Y, Ou M
American journal of translational research 2019;11(12):7591-7603
American journal of translational research 2019;11(12):7591-7603
Ginsenoside compound K ameliorates Alzheimer's disease in HT22 cells by adjusting energy metabolism.
Chen X, Li H, Yang Q, Lan X, Wang J, Cao Z, Shi X, Li J, Kan M, Qu X, Li N
Molecular biology reports 2019 Oct;46(5):5323-5332
Molecular biology reports 2019 Oct;46(5):5323-5332
Talin promotes integrin activation accompanied by generation of tension in talin and an increase in osmotic pressure in neurite outgrowth.
Wang Y, Zhang X, Tian J, Shan J, Hu Y, Zhai Y, Guo J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6311-6326
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 May;33(5):6311-6326
Receptor-Mediated Field Effect Transistor Biosensor for Real-Time Monitoring of Glutamate Release from Primary Hippocampal Neurons.
Li YT, Jin X, Tang L, Lv WL, Xiao MM, Zhang ZY, Gao C, Zhang GJ
Analytical chemistry 2019 Jul 2;91(13):8229-8236
Analytical chemistry 2019 Jul 2;91(13):8229-8236
The protective mechanism underlying phenylethanoid glycosides (PHG) actions on synaptic plasticity in rat Alzheimer's disease model induced by beta amyloid 1-42.
Jia JX, Yan XS, Song W, Fang X, Cai ZP, Huo DS, Wang H, Yang ZJ
Journal of toxicology and environmental health. Part A 2018;81(21):1098-1107
Journal of toxicology and environmental health. Part A 2018;81(21):1098-1107
Dental pulp stem cells promote regeneration of damaged neuron cells on the cellular model of Alzheimer's disease.
Wang F, Jia Y, Liu J, Zhai J, Cao N, Yue W, He H, Pei X
Cell biology international 2017 Jun;41(6):639-650
Cell biology international 2017 Jun;41(6):639-650
p-Glycoprotein ABCB5 and YB-1 expression plays a role in increased heterogeneity of breast cancer cells: correlations with cell fusion and doxorubicin resistance.
Yang JY, Ha SA, Yang YS, Kim JW
BMC cancer 2010 Jul 22;10:388
BMC cancer 2010 Jul 22;10:388
Parkin deletion causes cerebral and systemic amyloidosis in human mutated tau over-expressing mice.
Rodríguez-Navarro JA, Gómez A, Rodal I, Perucho J, Martinez A, Furió V, Ampuero I, Casarejos MJ, Solano RM, de Yébenes JG, Mena MA
Human molecular genetics 2008 Oct 15;17(20):3128-43
Human molecular genetics 2008 Oct 15;17(20):3128-43
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HT-1080 cells were subjected to SDS PAGE followed by western blot with 10274-1-AP(TAU antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 10274-1-AP(TAU antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TAU antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TAU. This antibody recognizes human, mouse, rat antigen. The TAU antibody has been validated for the following applications: ELISA, WB, IHC analysis.