Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15677-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- LZTS2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LZTS2 antibody (Cat. #15677-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Proximity proteomics identifies PAK4 as a component of Afadin-Nectin junctions.
β-Trcp and CK1δ-mediated degradation of LZTS2 activates PI3K/AKT signaling to drive tumorigenesis and metastasis in hepatocellular carcinoma.
LZTS2 inhibits PI3K/AKT activation and radioresistance in nasopharyngeal carcinoma by interacting with p85.
Baskaran Y, Tay FP, Ng EYW, Swa CLF, Wee S, Gunaratne J, Manser E
Nature communications 2021 Sep 7;12(1):5315
Nature communications 2021 Sep 7;12(1):5315
β-Trcp and CK1δ-mediated degradation of LZTS2 activates PI3K/AKT signaling to drive tumorigenesis and metastasis in hepatocellular carcinoma.
Lu Y, Li X, Liu H, Xue J, Zeng Z, Dong X, Zhang T, Wu G, Yang K, Xu S
Oncogene 2021 Feb;40(7):1269-1283
Oncogene 2021 Feb;40(7):1269-1283
LZTS2 inhibits PI3K/AKT activation and radioresistance in nasopharyngeal carcinoma by interacting with p85.
Xu S, Li Y, Lu Y, Huang J, Ren J, Zhang S, Yin Z, Huang K, Wu G, Yang K
Cancer letters 2018 Apr 28;420:38-48
Cancer letters 2018 Apr 28;420:38-48
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 15677-1-AP( LZTS2 Antibody) at dilution of 1:300
- Other comments
- WB
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LZTS2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LZTS2. This antibody recognizes human,mouse,rat antigen. The LZTS2 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human kidney tissue slide using 15677-1-AP( LZTS2 Antibody) at dilution of 1:50 (under 10x lens)
- Other comments
- IHC