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LearnNB100-294
antibody from Novus Biologicals
Targeting: AURKB
Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5
Western blot Immunocytochemistry Immunoprecipitation
Immunohistochemistry Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Chromatin Immunoprecipitation [1]
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- Product number
- NB100-294 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-294, RRID:AB_2061617
- Product name
- Rabbit Polyclonal Aurora B Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Aurora B
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 12.5 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references RecQL4-Aurora B kinase axis is essential for cellular proliferation, cell cycle progression, and mitotic integrity.
Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability.
Aurora B expression and histone variant H1.4S27 phosphorylation are no longer coordinated during metaphase in aneuploid colorectal carcinomas.
STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments.
Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation.
Aurora-B protein expression is linked to initial response to taxane-based first-line chemotherapy in stage III ovarian carcinoma.
Checkpoint-independent stabilization of kinetochore-microtubule attachments by Mad2 in human cells.
Expression of mitotic kinases phospho-aurora A and aurora B correlates with clinical and pathological parameters in bladder neoplasms.
Targeting Aurora kinases for the treatment of prostate cancer.
Fang H, Niu K, Mo D, Zhu Y, Tan Q, Wei D, Li Y, Chen Z, Yang S, Balajee AS, Zhao Y
Oncogenesis 2018 Sep 12;7(9):68
Oncogenesis 2018 Sep 12;7(9):68
Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability.
Dumitru AMG, Rusin SF, Clark AEM, Kettenbach AN, Compton DA
eLife 2017 Nov 20;6
eLife 2017 Nov 20;6
Aurora B expression and histone variant H1.4S27 phosphorylation are no longer coordinated during metaphase in aneuploid colorectal carcinomas.
Sijare F, Geißler AL, Fichter CD, Hergeth SP, Bogatyreva L, Hauschke D, Schneider R, Werner M, Lassmann S
Virchows Archiv : an international journal of pathology 2015 May;466(5):503-15
Virchows Archiv : an international journal of pathology 2015 May;466(5):503-15
STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments.
Kleyman M, Kabeche L, Compton DA
Journal of cell science 2014 Oct 1;127(Pt 19):4225-33
Journal of cell science 2014 Oct 1;127(Pt 19):4225-33
Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation.
Kabeche L, Compton DA
Nature 2013 Oct 3;502(7469):110-3
Nature 2013 Oct 3;502(7469):110-3
Aurora-B protein expression is linked to initial response to taxane-based first-line chemotherapy in stage III ovarian carcinoma.
Beussel S, Hasenburg A, Bogatyreva L, Hauschke D, Werner M, Lassmann S
Journal of clinical pathology 2012 Jan;65(1):29-35
Journal of clinical pathology 2012 Jan;65(1):29-35
Checkpoint-independent stabilization of kinetochore-microtubule attachments by Mad2 in human cells.
Kabeche L, Compton DA
Current biology : CB 2012 Apr 10;22(7):638-44
Current biology : CB 2012 Apr 10;22(7):638-44
Expression of mitotic kinases phospho-aurora A and aurora B correlates with clinical and pathological parameters in bladder neoplasms.
Bufo P, Sanguedolce F, Tortorella S, Cormio L, Carrieri G, Pannone G
Histology and histopathology 2010 Nov;25(11):1371-7
Histology and histopathology 2010 Nov;25(11):1371-7
Targeting Aurora kinases for the treatment of prostate cancer.
Lee EC, Frolov A, Li R, Ayala G, Greenberg NM
Cancer research 2006 May 15;66(10):4996-5002
Cancer research 2006 May 15;66(10):4996-5002
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Aurora B Antibody [NB100-294] - Rabbit polyclonal to Aurora B (NB100-294) used to stain SW620 human tumour xenografts (in mouse). The sections were microwave pretreated in citrate buffer (pH 6.0) for 5 mins high then 5 mins simmer (800W conventional microwave). Slides were then incubated for 1 hour with the Aurora B primary antibody diluted 1/200 in TBS, then visualised using DAB, after application of an appropriate secondary.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Chromatin Immunoprecipitation: Aurora B Antibody [NB100-294] - 293T cells stained with Aurora B antibody. Image from verified customer review.
